Because we fit almost three million hypothesis tests in this simulation study, we did not include the CIT tests in this investigation, restricting our attention to the computationally more efficient CMST tests.
The four major variables tested in this simulation: tree topology, placement of reference taxon, tree building algorithm, and substitution rate, are discussed separately as much as possible given their inherent interrelationships.
To test the performance on large indels, we applied ScanIndel and the other tools tested in the simulation data to this sample and compared their predictions with two curated reference sets: (i) 138 validated deletions from the literature; and (ii) 105 previously predicted novel sequence insertions identified by the 1000 Genomes Project (see " Methods" for details).
However, the likelihood of such still reasonably high test accuracy for correctly identifying absence of third-order selection bias, may be lower in both RCTs [ 15, 16] (and thus, the reported absence of selection bias in these trials less reliable) as the test accuracy identified in this simulation study may be artificially increased, owing to the stated limitations of the chosen study method.
Different numbers, dispositions and stabilities (open time) of these tubules were tested in the simulation (Table 1; Figure 6C F).
For simplicity only the SNPs with no missing values were tested in the simulation study, leaving 50 254 SNPs for inclusion.
Figure 4 Example test run: The cognitive engine in this simulation was set up to continually make a decision.
A straight-forward empirical and experimental test of this simulation result if, in fact, network size underlying a particular trait varies between species is to find two species with different-size networks, equalize additive variance for the trait, and then measure the response to selection.
In this simulation test, the critical value of the pore water pressure is about 4.0 kPa.
The charging rate of the ASTROD I test mass due to interplanetary electrons in this simulation is about −11% of the cosmic-ray protons at solar minimum, and over −37% at solar maximum.
