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This hypothesis requires testing in a prospective study.
Further rigorous clinical evaluation including testing in a prospective randomized controlled trial is required and planned.
More definitive assessment of the hypothesis that brain changes seen in depressed older individuals reflect early AD awaits testing in a prospective cohort study.
Thus it appears that this protocol may enhance the delivery of enteral nutrition; however, this finding requires testing in a prospective randomized fashion.
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The Braden scale was tested in a prospective multi-centre design.
However, the existence of any genotype-dependent difference has not been tested in a prospective clinical trial.
It was further tested in a prospective sample of patients and demonstrated strong associations with physical and mental health summary scores and with disease severity.
The effectiveness of EUS-FNA combined with high negative pressure (HNP) suction was recently indicated for tissue acquisition, but has not thus far been tested in a prospective, randomized clinical trial.
We tested in a prospective physiological study the hypothesis that continuous administration of NMB agents in mechanically ventilated children with severe acute hypoxemic respiratory failure (AHRF) improves the oxygenation index without a redistribution of tidal volume V T toward non-dependent lung zones.
However, this empiric usage has not been tested in a prospective controlled trial.
This hypothesis should be tested in a prospective trial.
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