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We also aimed to consider its suitability for testing in a large randomized study.
In this "how it was done" narrative review, we provide a description of, and context for, the early development of a conjugate vaccine targeting extra-intestinal, pathogenic Escherichia coli (ExPEC), from its creation in the laboratory to its testing in a large, first-in-human phase Ib trial.
We characterized temporal patterns of of syphilis testing in a large cohort of HIV patients in Ontario, Canada.
We were able to combine 3T MRI imaging with comprehensive cognitive testing in a large study drawn from an occupational cohort.
The association between low levels of Ch7CEP and response to anthracyclines is interesting; however, this study is underpowered and this would require testing in a large cohort.
The purpose of this study was to evaluate the association of prior concussion on baseline computerized neurocognitive testing in a large cohort of high school athletes.
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Nonetheless, it allows for estimating the best operating conditions to use for initial disruption testing in a large-scale high-pressure homogenizer of a similar operating principle as the French press.
Following testing in a larger group of children, we may also remove some of the items with large floor effects to improve the measurement properties.
Altogether, the results suggest that n-3 LC-PUFAs could modulate B-cell activity in humans, which will require further testing in a larger cohort.
Further development of the intervention and testing in a larger experimental trial are warranted to determine effects on behavior change and body weight.
The three genes were selected for further testing in a larger sample of 256 children.
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