The instrument has been tested for criterion validity in a normal population [ 22] and test-retest reliability in community-dwelling older adults [ 23] with excellent results.
The CSOM has not been formally tested for criterion validity, but has shown responsiveness with known analgesics [ 30] and a putative analgesic [ 1].
It was not possible to test for criterion validity because there was no accepted, valid carer experience questionnaire available with which PCQ-C could be compared.
To test for criterion validity, Fisher's exact test was used to compare responses for each item submitted by each participant to the investigators "gold standard" answers that were reached by consensus prior to beginning the trial.
Testing for the T criterion refers only to aquatic organisms.
Diagnoses were ascertained by the study team testing for DSM IV Criteria with standardized questions (SKID) whereby an MD confirmed all diagnoses.
We tested for these criteria in SPSS 14.0 by applying Student's t-tests (2-sided), Pearson's correlation coefficients and multiple regression analysis (with alpha = 0.05 for statistical significance).
All such putative pockets were tested for certain criteria such as size and volume, retaining only those that were likely to bind to small molecules.
All of the data were based on self-report, and none of the questions was tested rigorously for criterion, content or construct validity.
As the OIDP total scores were not normally distributed and because some groups comparisons undertaken involved relatively small cell sizes, tests for criterion and construct validity were non-parametric (Mann-Whitney and Kruskal-Wallis Test as appropriate).
