Many multiple testing correction methods have been proposed.
P values were corrected using the Benjamini and Hochberg false discovery rate multiple testing correction procedure.
This approach requires rigorous multiple testing correction.
Methods for multiple testing correction and their application are described.
We identified 3064 differentially expressed genes (p < 0.05 after multiple testing correction).
Multiple testing correction was done by using a false discovery rate approach49.
Dark grey shading indicates features that are only significant without multiple testing correction.
Importantly this approach incorporating subclonal mutations allows dozens of window pairs to survive multiple testing correction.
Multiple testing correction was performed by the Bonferroni procedure based on 101 tested genes.
Using only clonal mutations only a handful of loci survived multiple testing correction, (Supplementary Fig. 13a, Supplementary Data 11).
False discovery rate (FDR) multiple testing correction was also performed.
