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However, nonhematological toxicity of chemoradiation is substantial and different strategies should be tested to minimize it.
It has already been tested to minimize the energy consumption in intensified distillation sequences, but this work is an extension that includes the assessment of the process controllability.
Only a small number of all possible zones (potential clusters) are tested, to minimize multiple testing and false positives.
Whenever possible, multiple independent insertion lines and/or constructs were tested to minimize the potential issue of inefficient RNAi constructs.
Euclidean distances were used, and three sets of seeds were tested to minimize the impact of the starting values on the resulting clustering implemented using SAS [ 33].
Four goats were also tested at 14 wpv (the remaining goats were not tested to minimize the potential effect of the intradermal tuberculin inoculation on the IFN-γ assay).
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Plastic films were stored at −15 °C until testing to minimize aging effects (Srubar et al. 2012).
Subjects wore a lead-lined thyroid shield and protective vest during testing to minimize X-ray exposure.
Standardized handling protocols were administered three days before testing to minimize the influence of the experimenter.
Previous research has recommended that a practice period of 10 minutes is required prior to testing to minimize potential learning effects associated with treadmill walking [ 19].
We used an a priori defined set of reference genes with different physiological tasks (β-actin, histone H3, Grp78 and HIF-1α) for the stability tests to minimize the risk of choosing co-regulated genes.
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