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As more than one lifeform were tested, the lack of requirement for vitrification is unlikely to be due to a species or lifeform specific factor.
Since null alleles were available for only two of the 41 mutants tested, the lack of strong phenotypes for many of the tested genotypes could be due to incomplete loss of function (Table S1, column 9).
Although this cell line was responsive to low doses of the other drugs tested, the lack of activity of xanafide in the T47D could be, in part, due to its long doubling time.
While exposures to high lead-in-dust and yard soil are of concern for six of the fourteen homes tested, the lack of standards for mold and PM in the home environment makes interpretation of those data problematic.
Although potential for nonlinearities in the PK model (e.g., Michaelis Menten elimination) was not tested, the lack of bias in the diagnostic plots suggested that a linear PK model adequately described the data and that TAK-875 exhibited linear PK over the evaluated dose range.
It is undoubtedly true that our array does not include all the genes of relevance to the drugs tested – the lack of good correlation with some agents may reflect this, or general resistance that would result in poorer correlation due to a lack of heterogeneity.
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We test the lack of autocorrelation of the residuals following estimation using Wooldridge's (2002) panel serial correlation test.
The CCD is an effective design that is ideal for sequential experimentation and allows a reasonable amount of information for testing the lack of fit while not involving an unusually large number of design points.
For 7 out of the 8 tested accessions, no pollen incompatibility was observed: consequently the cross with rpt5a-4 mutant could be used to test the (lack of) complementation of the rpt5a mutation.
Physicians who would not try to persuade a patient to be tested questioned the lack of scientific evidence and efficacy of the PSA test.
Yet that passion for the job is being tested by the lack of recognition and support at a national level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com