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"I'd feel better if we'd gone in after they'd tested it more," said Specialist Jake Herring, 20, of Kirkland, Wash.
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Recent advice about designing and evaluating complex interventions suggest that it is important to evaluate the design and its implementation before testing it more rigorously in a randomized controlled trial [ 17].
Also, this will suggest ways of testing it more searchingly.
But it seems a plausible hypothesis, and the tools to test it more thoroughly are now in place.
We're working on a study on this, in northern Uganda, where we had a chance to test it more closely.
At present, clinical investigators are able to make only intuitive assessments of children's competence, because no standardized method is available to test it more objectively.
Recent advice about designing and evaluating complex interventions, suggests that it is important to evaluate the feasibility of both the design and the implementation of a complex intervention before testing it more rigorously in a randomized controlled trial [ 32].
Whenever more fine hypotheses are to be tested, it makes more sense to turn to methods that allow more flexible modeling of the covariance structure and provide associated tests of hypothesis or pointwise estimation.
He also said the company spent 14 years developing the vaccine and tested it in more than 50,000 children, which drove up the cost.
We developed a "double cropping system" and tested it for more than 10 years in field experiments.
That's all the proof I really need and there's no test that could prove it more effectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com