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We conclude that the removal of a single acetylation site on H3 (either K14 or K36 was tested) is sufficient to cause an alteration of nucleosome occupancy within the promoter resulting in a defect in ste11 transcription.
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Surprisingly, directing Grb2 predominantly to a single pY site of the Ptpn11/Shp2 phosphatase, but not other sites tested, was sufficient for differentiation of the essential primitive endoderm lineage from embryonic stem cells.
In all the performed experiments the heat production rate by the living organisms tested was sufficient to produce a detectable signal over time.
That does not entirely eliminate the farm as the outbreak's origin, since even one positive test is sufficient to make the connection.
This provides a means to determine whether the amount of project-specific information (e.g., in-situ and/or laboratory tests) is sufficient in site characterization.
One strain controlled temperature increase test is sufficient to determine the temperature for onset and most pronounced influence of dynamic strain aging, i.e. the reduction of dislocation mobility due to diffusing interstitial atoms.
Some suggest that an ACTH stimulation test is sufficient as first-line investigation, and that an insulin torlerance test is only needed if the ACTH test is equivocal.
In areas of the world were rheumatic fever is uncommon, a negative rapid strep test is sufficient to rule out the disease.
We previously demonstrated that this panel of immunological tests is sufficient in identifying even subclinical levels of autoimmunity that predisposes towards POA/OPOI [25], [26].
A numerical test shows that Nsim = 24, which value we employed previously [13] without rigorous testing, is sufficient, because the results of the energy minimization cease to depend on Nsim beyond this number (Fig. 1).
Instead, implementation of a single genetic test is sufficient.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com