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In the light of recent data from the ASCO 2012 Annual Meeting, PI3K and MEK inhibitor combination treatments are now being tested in concurrent and intermittent schedules [ 22, 23].
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All serum samples were tested in duplicate with a concurrent positive control and a minimum of four negative (Dutch blood bank donor) controls per plate.
The gray curves show the normalized spatial tuning of the same neurons measured with an additional concurrent sound at another location (nine different locations of concurrent sounds were tested in total).
The wording, sequences and its concurrent validity were tested in the clinical and community population.
The final product (Hausa IPAQ-SF) was tested in a cross-sectional study for concurrent (correlation with the English version) and construct validity, and test-retest reliability in a sample of 102 apparently healthy adults.
In oesophageal cancer, cetuximab has been tested in combination with irinotecan, cisplatin and concurrent radiotherapy in Phase II studies: a single centre study (NCT00165490, 02-012) and in the SWOG-SO414 study.
In this concurrent choice paradigm, mice were tested in two conditions termed 'choice' and 'no choice' on alternating days.
Therefore, taxane-based regimens should be tested in a randomised trial and compared with a less intensive concurrent regimen.
However, a concurrent DUR strategy, with direct feedback to prescribers seems effective and should be tested in other settings with other drugs.
Currently, this hypothesis is being further tested in clinical trials in which patients with metastatic NSCLC are treated with standard cisplatin and docetaxel plus concurrent imatinib.
All treatments were tested in 0.85% NaCl solution Fig. 2 Viability of S. mutans biofilm cells after treatment with CHX, DC, or concurrent treatment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com