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A critical level of air relative humidity was required to generate porous particles for each tested formulation.
Drug content (0.2 1.51%) and controlled release properties were related to the influence of all tested formulation factors.
Behind the important nutritional/bioactive composition of G. lucidum, a potential towards its valorisation in the field of cosmeceuticals is foreseeable, as deduced from the bioactivities of its ethanolic extract and preservation in the tested formulation.
Subsequently, by means of a single quantitative technique, we were able to follow, for each tested formulation, major steps of the NP-mediated gene delivery process – NP cell membrane association, internalization and intracellular trafficking, including plasmid DNA transport towards the nucleus.
It also appears here that prochloraz is the main toxicant of the tested formulation.
The only new clinically tested formulation approved by the FDA in recent memory has been Colgate Total, approved in 1996.
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Site 1 sodium channel blocker and dexmedetomidine formulations were not cytotoxic and corneal healing was not delayed significantly by any of the tested formulations.
There was a significant difference (P⩽0.05) between the predicted optimum and the other two tested formulations.
Overall, FA release was sustained in vitro over almost 400 days by all tested formulations.
All the tested formulations presented a mucoadhesion time of greater than 12 h.
Interestingly, among all tested formulations, niosomes elaborated with squalene as helper lipid were the most efficient transfecting cells.
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