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Each locus was tested for deviation from Hardy-Weinberg equilibrium and linkage disequilibrium with other loci (p < 0.05) using the program Genepop [ 64].
Genotype frequencies were tested for deviation from Hardy Weinberg equilibrium (HWE), and genotype checks were conducted for SNPs that deviated from HWE.
Allele frequencies were estimated by gene counting and tested for deviation from Hardy-Weinberg equilibrium.
The observed genotype frequencies were tested for deviation from the Hardy-Weinberg equilibrium.
All SNPs were tested for deviation from Hardy-Weinberg equilibrium within the entire skin cancer case-control data set.
Genotype frequencies in sub-cohort individuals were tested for deviation from HWE using Pearson's chi-square test statistics with 1 degree of freedom for bi-allelic variants and 3 for three-allelic variants, applying a threshold of p<0.01.
Residuals of HW and TL, and SVL were tested for deviation from normality with Shapiro-Wilk tests, and Bartlett's tests were used to test for heteroscedacity (both tests α = 0.05).
We tested for deviation from random in phylogenetic dispersion in community composition for each plot based on the 48- species pool used at the start of the experiment, given the almost-random procedure with which the species compositions were initially set up by the BIODEPTH groups.
Each SNP was tested for deviation from Hardy Weinberg equilibrium.
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For linear and multiple linear regression, we tested for deviation of distributions of residuals from a normal distribution using the Shapiro-Wilk test.
For genetic analyses, all single-nucleotide polymorphisms evaluated will be tested for deviation from Hardy Weinberg equilibrium with the use of χ tests.
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