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With limited access to Kv1.1 null mice we tested for confirmation of some of the findings in mceph/mceph.
Our finding of 12 metabolites associated with age in men was not yet tested for confirmation.
Seventy-nine of 236 positively screened samples could not be tested for confirmation.
Putative de novo CNVs were tested for confirmation using qPCR (see Supplementary Information for more details on the qPCR replication).
Traits were tested for confirmation to normality (Kolmogorov-Smirnov and Lilliefors tests) and normalized as necessary with standard transformations.
If possible de novo CNVs were detected, these were tested for confirmation using qPCR (see Supplementary Information for more details on the qPCR replication).
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Milk samples were put to biochemical identification of Staphylococcus aureus and later oxacilline disk sensitivity testing for confirmation of MRSA.
Serum samples showing positive GMI were re-tested for confirmation.
All samples initially identified as positive for the mecA gene were re-tested for confirmation.
Positive results can be followed up with more specific testing for confirmation of the diagnosis.
This included HIV enzyme-linked immunosorbent assay (ELISA) testing with confirmation by ELISA on a second specimen for patients ≥18 months of age and qualitative HIV PCR testing for confirmation of HIV-infection status in children <18 months of age.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com