The majority of the anions tested display weak (mM) inhibition but some, such as the metal poisons and anionic acids, exhibit stronger (μM) inhibition.
The results indicate that all compounds tested display competitive inhibition in both the MAMC and dextromethorphan assay, and the Ki values reveal a very good correlation (R2=0.984) between the two assays.
To study how pVII and pIX perform in phage display of folded domains, we tested display of three different folded domains and compared with conventional pIII display.
The bone substitutes tested display a wide range in structural properties and compression strength, indicating that they will be suitable for different clinical indications.
In good correlation with the genotypes observed, we show that three out of the 14 mutants tested display between 17 and 42% residual activities compared with the wild-type enzyme, whereas the remaining 11 showed no activity.
The results presented here nevertheless show, that some of the promoter elements tested, display similar behavior whether analyzed in the context of Ptet promoters or in their original promoter environment.
