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For example, the "MeSH Term Tested" index retrieves assay records in which any tested compound is annotated with the query MeSH term.
Out of the 30 compounds tested, compound 19a, 19b, 25a, 25b exhibited significant anti-inflammatory activity.
Among the compounds tested, compound 16l demonstrated high inhibitory activity against SGLT2 (IC50 = 1.9 nM) with an excellent pharmacokinetic profile.
Among the compounds tested, compound 7 also had the highest prophylactic antiarrhythmic activity in adrenaline-induced arrhythmia in anaesthetized rats.
Moreover, all tested compound, at 50 μg/mL concentration, significantly reduced oviposition of adult worms in vitro.
The cell cytotoxic effect of each tested compound was calculated.
The results revealed that the tested compound showed a concentration-dependent reduction of 3Cpro.
The cytotoxicity of each tested compound was calculated [24, 25, 27, 28].
Each of them was dosed with a tested compound at 25 mg kg−1 via oral administration.
The IC50 values of the tested compound were estimated using the best fit regression curve method in Excel.
Also, none of the tested compound exerts any activity against the pathogenic yeast species ( C. albicans) under these screening conditions.
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