We then assessed whether test-retest variability and accuracy for determination of proliferation of the population input functions were affected by this reduced sampling population-based methodology.
This technique is non-invasive and has high accuracy, test-retest reliability and face validity [ 10].
The purposes of the present study were (a) to evaluate the performance of several PET-based PVC methods for oncological whole-body FDG PET studies and (b) to study the effects of PVC on SUV accuracy, test-retest variability and observed SUV responses.
Detailed evaluation experiments on more than 1000 subjects, including comparisons to FSL FIRST and FreeSurfer as well as a clinical assessment, demonstrate high accuracy and test-retest consistency of the presented segmentation approach, leading, for example, to an average segmentation error of less than 0.5 mm.
In a sample of Australian adolescents, the BPQ was found to have high internal consistency, diagnostic accuracy, high test-retest reliability, and moderate sensitivity [ 44].
4 5 Yet, several studies have shown that one-dimensional M-mode (1-DE) and 2-DE had limited test-retest reproducibility and that their accuracy was impacted by many factors including image quality, foreshortening of the LV cavity and geometric assumptions regarding LV volumes calculation.
The SIAS has demonstrated good internal consistency, test-retest reliability, convergent validity and diagnostic accuracy [ 13, 28, 29].
The results in this paper demonstrate that both image- and reconstruction-based PVC can be applied to improve SUV accuracy without worsening test-retest variability.
The latter is relevant not only for high accuracy, but also a good test-retest variability [ 31] is needed to detect metabolic responses [ 11, 17].
PVC improves accuracy of SUV without decreasing (clinical) test-retest variability significantly and it has a small, but significant effect on observed tumour responses.
