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As a first test, we sought to examine the effects of alanine substitutions on another Rsp5 substrate.
For our second test, we sought to test the correlation of miRNA to target mRNA between species.
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By using a computational simulation compared to mechanical tests, we sought to investigate the characteristics of stress-induced suture material on porcine myocardium.
To determine the most appropriate way to conduct association tests we sought not only to identify units of within-population structure but also the uniformity of differentiation throughout the genome between such units.
In these tests, we sought to recover known input parameters from the simulated data, to validate the BSA approach.
Since gene expression discovery studies may suffer from false positives, despite the use of statistical corrections for multiple hypothesis testing, we sought out independent validation of the primary findings of the CardioGene Study in a separate cohort.
Since no single gene harbored enough variants across sufficient number of isolates for direct testing, we sought to determine if there was enrichment across all virulence-associated genes classified as being involved in "pathogenesis" or "toxin production and resistance" by the JCVI CMR database [ 20].
Having demonstrated that TSLP was the most effective cytokine adjuvant of those tested, we sought to compare it with CT a mucosal adjuvant commonly used in murine studies 3, 5. Mice were immunised three times i.n. with 10 μg gp140 alone or with 5 μg TSLP or CT.
In order to develop an evidence-based approach to polar body testing, we sought to determine how often embryos that possessed isolated reciprocal aneuploidies in their polar bodies were actually euploid, reflecting PSSC in meiosis I with compensation in meiosis II.
Using these test strains, we sought to establish a cell death assay that invariably distinguishes the survival of these test strains from wild type under any given condition.
To test this we sought ways to induce cytosolic PrP localization in cultured CGN.
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CEO of Professional Science Editing for Scientists @ prosciediting.com