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In this test we observed robust activity of wt hAID on substrates containing multiple C residues and undetectable activity of the N51A mutant on these substrates.
In the marble burying test, we observed a significant increase in anxiety-related marble digging behavior in alcohol-withdrawn mice compared to naive mice, and this increase was prevented by tandospirone pre-treatment (Fig. 1B).
To our delight, in an initial test, we observed the formation of a TMM-containing spiro intermediate and its conversion into compound 3 in which the aryl carbon nitrogen bond was inserted by the TMM group and the para-benzylic carbon hydrogen bond was functionalized by methoxylation under acidic conditions.
By applying a Student's t test, we observed that, considering smaller neighbors values (k={20,40,60}), both term-based techniques produced statistically better results than the others, using a p value <0.005.
In acute toxicity test we observed that oral administration of MEPH did not produce any visible sign of delay toxicity, behavioral changes, allergic manifestations (skin, rash, itching), and mortality during the observation period of 72 h.
Using the allelic chi-squared association test, we observed significant association between rs8050136 and rs3751812 and risk for childhood obesity.
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From this test we observe that numerical solutions based on the Lax Friedrichs, the MacCormack and the Lax Wendroff break down easily.
For time-domain stacking, similar to the point source synthetic test, we observe a strong swimming effect at periods longer than 2 s.
Using McNemar's test, we observe that the proposed SQRT threshold resulted in significantly fewer mis-classifications than other thresholds (maximum P value, P=0.001 and minimum P value, P=3.83932E−28).
Using our science-process skills test, we observe a statistically significant increase in students' ability to propose an experiment that matches the goal of investigation.
By numerical tests we observed the expected high spectral accuracy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com