It should be noted that in vivo scenario is quite complex and the final outcome of the infection is dependent on the concerted action of several cell types such as epithelial cells, alveolar macrophages, neutrophils and lymphocytes, all of them expressing TLR2, recruited and/or activated upon infection whereas here we have just tested the interplay between A. baumannii and airway epithelial cells.
Before presentation of the structure of the paper, it is worth clarifying why such an experiment would be a test of quantum mechanics in a curved background, i.e. a test of the interplay between quantum mechanics and general relativity.
To further test this, the interplay between the various Maf1 kinases and PP4 in favourable versus unfavourable growth conditions should be investigated.
Thus, it would be interesting to test the possible interplay between MED23 and any nuclear receptors under metabolic regulation.
In this spirit of constructive refereeing, the take-home message, in my opinion, is to test the possible interplay of the antisense protein-coding gene and the NKILA noncoding RNA, and urge you to engage in such experimental approaches to push science forward.
By embedding biologically sensible growth equations into the mapping framework, functional mapping can estimate the dynamic changes of the genetic effects of a QTL in development and push hypotheses tests towards the interplay between genes and development.
Tests of the interplay between the two pathways on Sox1 GFP expression (supplementary material Fig. S1) indicate a predominant role of an inhibitory function of these signals, with the effects of Activin and Chi being dominant over the loss of function of either pathway.
Dolan shouted, "She's got a brain!" Machado also performed a test that measures the interplay between the sympathetic and parasympathetic nervous systems, a relationship that regulates states of arousal and rest.
This result demonstrates the increased power afforded by the set test owing to the interplay of SNPs within the gene that is missed by a univariate approach.
However, more data would be required to test this interplay between shifts of global circulation patterns and reassortment, or, alternatively, the hypothesis that global continuous circulation prevents the emergence of highly pathogenic strains by eliminating chance reseeding.
