Sentence examples for test the functional consequences from inspiring English sources
Ultimately, it will be important to test the functional consequences of these results, such as the effect of RIPs on gene function, and their role in cancer and neurological disorders.
We used primary human nasal epithelial cell (HNEpC) cultures to test the functional consequences of Wnt pathway activation.
To test the functional consequences of the mutated F2 in enhancer blocking we introduced this mutation into the F1F2 enhancer blocking construct.
A high-throughput platform has been used to interrogate the entire FLT3 coding sequence in AML patients and experimentally test the functional consequences of each candidate tumorigenic allele [63].
To test the functional consequences of the transferred H-RasG12V in the adopting lymphocyte, we recorded phospho-ERK (pERK) levels as readout of the activation of the Ras/Raf/MEK/ERK cascade in NK cells that were co-cultured with B721−GFP-H-RasG12V.
To test the functional consequences of CXCR2 down-regulation, an in vitro chemotaxis assay was performed.
In order to test the functional consequence of the Nef:MHC-I complex trafficking through early and late endosomes, we designed a lentiviral vector that expressed Flag-tagged MHC-I simultaneously with HIV-1 viral proteins (Fig. 5e).
To test the functional consequence on enhancer blocking by the mutated binding site, we performed transfection experiments with episomes containing the F1F2 or the F1mutF2 binding sites.
To test the functional consequence of miR-155 expression, PBM were transfected with either exon 3 of BIC (encoding the mature miR-155) or an empty vector.
To directly test the functional consequence of T cell LFA-1 overexpression, a murine CD18 construct (CD18/pSub2) was transfected into D10 cell.
To test the functional consequence of this SNP as well as demonstrate direct interaction between miR-517a/c and TNIP1, we cloned sequences containing the major and minor alleles immediately downstream of a firefly luciferase reporter.
