In the screen reported herein, we tested the Diversity Set of the NIH/NCI chemical library, and identified four compounds with pronounced proteasome inhibitory activity, three of which are novel inhibitors.
Dybzinski et al. [15] further tested the diversity effect on plant productivity by investigating the fertility of soil beneath plots of varied levels of diversity and found that more diverse plots can support increased productivity via greater nutrient retention and inputs.
Strengths of this study include the large data sets available for testing, the diversity of the samples with regard to age, health status, work status, culture, and gender.
The G test analyzes the diversity of diploid populations on multi-loci where multi-allelic possibilities exist and tests the null hypothesis that the distribution is identical across populations [ 10].
In this context, it is important to test if the diversity of other genes playing a role in glucose metabolism, such as SLC2A4, also bears the signature of natural selection.
For this purpose, a Mantel test comparing the diversity matrices of the phenotypic and genotypic data was performed.
Specifically, we used AMOVA to test if the diversity in groEL was differentially distributed with respect to host mtDNA haplogroups.
Initially 14 isolates were chosen to test the genetic diversity of the spacers: Nine Mile, Priscilla, Q212, Heizberg, Brasov, Dog ut Ad, CB15, CB20, CB26, CB28, CB33, CB35, CB114, and CB115.
Rates of recruitment, participation, and follow-up testing, and the diversity of participation in our study were substantially higher than what is generally considered achievable for this type of CE[25].
Thus, for the PBZ1 gene, the observed correlation between constitutive expression and partial resistance holds true for almost all the 23 rice genotypes tested, despite the diversity explored.
