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To test the action of antidepressants on CRE/CREB-directed transcription CRE-Luc mice were treated acutely (24 h) and chronically (21 days) with imipramine (Table 2).
Attempts to test the action of Cezanne on prolyl mutant HIF-1 α have so far been unsuccessful.
Animal models of disease provide an important opportunity to test the action of existing drugs in new disease contexts.
Therefore, further research is required using some or all of these theories to test the action strategies identified in the outcome map.
They can thus be used to study tumour biology, initiation and progression, and to test the action and efficacy of anti-cancer drugs at various time points during disease progression.
We suggest that animal disease models such as this provide an important opportunity to test the action of available drugs in disease contexts that would otherwise remain unexplored in the drug development industry.
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High-throughput screening uses robots to test the actions of thousands of compounds against a molecular disease target (itself identified by genomics).
Due to this controversy, we asked whether an in vitro bioassay can be designed to test the actions of drugs directly onto neuronal activity.
We tested the action database on action classification tasks and human body posture inference tasks.
We also tested the action of lidocaine under pathological conditions.
Every intended action, or decision, is preceded by an unconscious process of "trial action", testing the action for its consequences, to receive back a judgment of safety or danger.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com