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For new drugs to be acceptable in the current field, they will have to pass a litmus test of tolerability.
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While this - in all likelihood - did not impact the testing of the tolerability of NCT, a reliable evaluation of its efficacy turned out to be impossible within that observation period.
There were also differences in terms of perceptions of test tolerability (p < 0.0005).
The patients were previously healthy volunteers who participated in a study, conducted by Biotrial, a private company in the city of Rennes, to test the tolerability of a candidate drug.
Recently, the pig model proved to be very suitable and sensitive to test the tolerability of inhaled NCT [ 8].
It was not an objective of the study to compare the effect of the different CIGB-300 doses among them but to test each one in terms of tolerability and a preliminary efficacy evaluation.
Wireless esophageal pH monitoring system is an important approach for diagnosis of gastroesophageal reflux disease (GERD), the aim of this study is to test the tolerability and utility of the first wireless esophageal pH monitoring system made in China, and evaluate whether it is feasible for clinical application to diagnose GERD.
45 The full blood count, liver function test and kidney function test are to assist with safety monitoring and assessment of tolerability of RCM-106.
Therefore, the idea of oral administration of cisplatin was worth testing in order to investigate its level of tolerability.
The Wilcoxon signed rank test was used to analyse the global assessment of tolerability expressed by patients.
A Phase 1 clinical trial was designed to test safety, tolerability, and antiviral activity of HCV-AB68 in patients with chronic HCV-infection.
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