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In order to maximize the flexibility with which models are assessed, no formal test of interaction is performed.
In order to accomplish a valid test of interaction, a straightforward extension to the MDR-PDT and MDR algorithms is implemented.
The validity of the proportional hazards assumption was evaluated via a test of interaction between HPV status indicators and duration of follow-up.
We demonstrate with simulation that fitting a regression model on the same data as that analyzed by MDR or MDR-PDT is not a valid test of interaction.
The difference between the estimates of 2 subgroups was evaluated by conducting a test of interaction based on meta-regression models [30].
A test of interaction was performed using likelihood ratio test.
The statistical test of interaction is a useful tool in this dilemma.
f P value for difference between ESRF and non-ESRF models (test of interaction).
p value for test of interaction effect between the PRE and SE regimens.
Multivariate linear regression analysis was performed to adjust the potential confounders and test of interaction.
The test of interaction was marginally significant (p = 0.05, Table 3).
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