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"This is very much a test of concept," Graham told the Guardian.
Our experiments showed the following for our test of concept experiment:.
Moreover, the authors performed a mediation analysis to demonstrate that the activation in the primary motor cortex accounted for the between-group performance difference on the test of concept understanding (Kontra et al., 2015).
Because it was so small, however, and involved alarms played at levels about four times louder than those in most homes, Smith described it to HuffPost as simply a basic test of concept.
Importantly for the co-variance argument raised above, IL-4 also increases the expression of CB1 receptors in lymphocytes [27], [28] so we elected to focus on that molecule as a "test of concept" that a component of the tumour microenvironment can influence FAAH activity.
As a test of concept, this proposed neurodegenerative process might be investigated clinically by taking advantage of the differing actions of the cholinesterase inhibitors that are widely used in the hope of achieving symptomatic benefits for AD patients.
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In the Step Vaccine Study, a phase II test-of-concept study trial of the Merck HIV-1 gag/pol/nef vaccine, men who have sex with men (MSM) with previous exposure to HAdV-5 through natural infection appear to have had at least transiently increased risk of acquiring HIV after vaccination [15], [20].
Also, although useful as a test-of-concept, the results from the HIV-related lymphoma population may not necessarily translate to the treatment of other HIV/AIDS patients targeted for studies testing gene therapy products and non-myeloablative conditioning regimens.> The endpoint of anti-HIV-1 trials require an antiviral effect measured by HIV-1 RNA plasma levels for demonstration of efficacy.
An exploratory randomised controlled trial was conducted to test proof of concept of RESTORE: a web-based tool to enhance self-efficacy to manage cancer-related fatigue.
"It is the department's intention to trial within the next 12 months, a pilot of up to 1,000 desktops to test proof of concept for open source," a DWP spokeswoman told GGC.
This was a pilot study to test proof of concept for an automated two-way text messaging service to support women to breastfeed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com