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Fig. 2 The effect of MEPH on the hole cross test (number of hole crossed at 0 min, 30 mins, 60 mins, 90 mins and 120mins) in mice Table 3 The effect of MEPH on hole cross test in mice Treatment Dose (mg/kg) Number of holes crossed 0 min.

Fig. 1 The effect of MEPH on the open field test (number of square crossed at 0 min, 30 mins, 60 mins, 90 mins and 120 mins) in mice Table 2 The effect of MEPH on the open field test in mice Treatment Dose (mg/kg) Number of squares crossed 0 min.

A logistic regression analysis for positive TST results (induration≥15mm) and for positive blood assay results was performed to adjust the potential confounding factors including age, prior tuberculin skin test, number of BCG scars, student category and increase in the interleukin-10 concentrations when exposed to either of the antigens.

† Mann Whitest-U test, number of medical providers = 14.

Comparisons were assessed using McNemar's χ2 test; Number of trios = 149.

S1.A Mealiness score and results of the cell cohesion test (number of cell per μl).

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Differences between groups of patients were tested (two-tailed) by using Fisher's exact test (sex, type of hospital, type of diagnosis, having a complication), Pearsons χ2 test (ICD-9 code), Median Test (median age, median duration of admission) or a t-test (number of complications).

Differential expression values, false discovery rates, and p-values were calculated with the "ComparativeMarkerSelection" module (test direction  = 2-sided, test statistic  =  T-test, number of permutations  = "0", complete  =  no, balanced  =  no, smooth p values  =  yes).

Using a difference score as the criterion in a within-subject t-test, the mean difference between pre- and post-test number of questions answered correctly was 4.08 out of 9.00, a statistically significant result with a 95% CI of 3.44 4.72 (p < 0.0001).

Activated DCs (either by LPS or by iHIV) consistently induced markedly enhanced proliferation of CMV-specific CD4+ T cells compared to non-activated DCs (Fig 6A C) (p < 0.05, paired t-test; Number of individuals tested N = 3), indicating that also antigen-experienced CD4+ T cells profit from the activation status of DCs, in particular under limiting antigen concentrations.

Analysis with Independent Samples T-test did not reveal any significant differences between the groups at baseline regarding age, degree of depression, stress, energy, ongoing pain, affective personality (PANAS-test), number of sleeping hours, minutes awake before falling asleep, experienced sleep quality, consumption of nicotine (cigarettes/snuff) or alcohol (ps > 0.11).

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