Sentence examples for test guideline from inspiring English sources
As alternatives to the Draize test, the BCOP test (OECD Test Guideline 437), the ICE test (OECD Test Guideline 438), and the Fluorescein Leakage test (TG 460) have found acceptance in regulatory toxicology.
In an algae growth inhibition test (OECD test guideline 201) the WSF did not affect the growth of Chlorella vulgaris.
However, notwithstanding this relevance, no test guideline is available by now and only very few institutions have spent research effort on cyclic R curves so far.
Furthermore, acute and reproductive toxicity tests (OECD test guideline 202) carried out using Daphnia magna did not indicate any deleterious effect of the WSF.
Although an internationally-adopted in vitro dermal absorption test guideline is available (OECD Test Guideline 428), the replacement of the in vivo approach in North America for pesticide formulations has not occurred due to concern over the reliability and consistency of the in vitro results.
"We do not believe that the proposed validation study will result in a technique that could be routinely used in a test guideline and would provide a reliable endpoint for regulatory risk assessment," she wrote to the international standards-setting group.
The extended one-generation reproduction toxicity study (EOGRTS; OECD test guideline 433) is a new and technically complex design to evaluate the putative effects of chemicals on fertility and development, including effects upon the developing nervous and immune systems.
In the present study, we have explored the usefulness of including immune parameters within the prenatal developmental toxicity study in rats, using the treatment protocol as described in the OECD 414 developmental toxicity test guideline.
Our experiments showed that OECD Test Guideline No. 222 (Earthworm Reproduction Test) can be used to test solid nanomaterials and that the preparation of test materials using 1% dry soil as a carrier is a suitable application method.
We conclude that TiO2 nanomaterials can affect earthworm reproduction if the test is carried out according to OECD Test Guideline No. 222 using natural sandy soil.
