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Our comparative examination of these methods suggests that continued research into methods that test for interacting loci is necessary to expand the tools available to researchers and to achieve improved power for detecting complex interactions, along with accurate assessment of statistical significance.
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We next tested which region of USP15 is responsible for interacting with BARD1 by expressing BARD1 together with USP15 or its truncated mutants in HEK293T cells (Fig. 2c).
What was the etiquette for interacting with Alexa?
PFAM domains for interacting pairs.
User interface (for interacting with users).
Another is necessary for interacting with thrombomodulin.
Only when the test for interactions was significant (P < 0.05), we looked at the pair-wise hazard ratios for assessing effects of interacting variables.
This is a novel phenotypic aspect of TDP-43 and can provide a useful assay for testing candidate interacting genes and small molecules with therapeutic potential for ALS.
Control experiments were conducted in parallel using deactivated amino-link beads to test for proteins that interacted nonspecifically with the resin.
When testing for multiple interacting pairs, iLOCi has high accuracy under the conditions of high heritability and informativeness, i.e., low MAF.
To address whether ARTD10(435–528) can interact with karyopherins, we have begun to test for direct interaction.
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CEO of Professional Science Editing for Scientists @ prosciediting.com