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The diagnosis is based on a blood test for excess levels of a hormone called 17-hydroxyprogesterone — there is also a genetic test — and treatment involves small doses of the steroid dexamethasone.
Similarly, nested RT-PCR by PfuUltra is expected to generate a total error rate of ∼7.54×10−5 per bp (i.e., one error in 13,263 bp), which was used to test for excess mutations observed in the cloned-sequenced RT-PCR products assuming Poisson distribution (Table S2).
To test for excess of insertions/deletions in STRs, we used a binomial test.
The GIF test for excess relatedness was performed for the 36 different cancer groups shown in Table 1.
The bottleneck program [ 40] was used as an alternative measure of genetic bottlenecks to test for excess gene diversity relative to that expected under mutation-drift equilibrium.
Following Seehausen [ 51], we applied a tree-based method to test for excess homoplasy in our dataset, possibly introduced by taxa of ancient hybrid origin.
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We used the HKA test for excesses of variation in SDHA gene.
Consequently, the plausible effects used are conservative in testing for excess statistical significance.
One limitation of the TDT (and tests for excess allele sharing) is that even relatively low levels of genotyping error can strongly enrich for apparent TD.
B ottleneck tests for excess heterozygosity using several mutation models including the stepwise mutation model (SMM), infinite allele model (IAM), and a two phase model (TPM).
CPBA not only provides a sparse parametrization of a general similarity matrix, but it also identifies hub nodes and clusters and enables significance tests for excess edges (between nodes) and shared similarities (between clusters).
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