The new test extracts the DNA for the APC gene, both from normal and cancerous cells, and makes the DNA manufacture protein.
The test extracts had a variable effect on the organisms (Fig. 2a f).
All the test extracts showed significant DPPH and ABTS radical scavenging activity in comparison with BHT.
Therefore, among all the test extracts, methanol was most potent against both bacteria and fungi (Table 4).
The higher concentration (5 mg/ml) test extracts kill all the worms at 60 min of incubation time.
A qualitative phytochemical study was conducted to know the presence or absence of phytoconstituents in the test extracts.
By comparing the areas of zone of inhibition of test extracts with standard, the concentration and potency of test samples were determined.
The remaining five of the 16 test extracts from A. membranaceus, S. ningpoensis, C. chinensis, P. verticillatum, Agrimonia pilosa were found to be ineffective as anti-insulin resistance agents in DXMS-induced IR HepG2 cells.
Encouragingly, no re-growth was observed in any test organism against all the test extracts, i.e., the extracts exhibited bactericidal nature, which will be quite useful when considered for drug development purpose.
Therefore, the active components in test extracts may increase glucose uptake of living cells and at the same time the toxic components in the extract reduce the number of living cells.
In case of UTI and RTI bacteria, all the extracts exhibited MBC/MIC ratio less than "32", which indicated that the test extracts of B. monnieri were bactericidal rather than bacteriostatic.
