While CellSearch™ is the only FDA-approved test for enumeration of CTCs, other CTC capture and characterization technologies, including single cell analysis, are rapidly advancing [ 43- 46].
Statistical analyses were done with the SPSS software 17.0 (using fisher exact test for enumeration data, employing t-test for means comparison between two groups, applying one-way analysis of variance for means comparison among multi-groups).
Investigations included; interviews, physical examinations, HIV testing and enumeration of CD4+ T cells.
Chapter 2.6.12 Microbiological examination of non sterile products: Microbial enumeration tests and Chapter 2.6.13 Microbiological examination of non sterile products: Test for specified microorganisms.
In pharmaceutical manufacturing, the majority of microbial enumeration test samples are filterable liquids or environmental (air and surface) samples.
Our goal in developing the technology described here is to provide a microbial enumeration test that is faster than visual plate counting, but maintains the advantages of the traditional method.
Among several methods developed for CTC detection, the CellSearch® system (Veridex LLC, Warren, NJ, USA) is the only US Food and Drug Administration-cleared test for CTC enumeration in clinical practice [ 12].
The analyses were carried out using the Tempo System (automated quality indicator solution; bioMérieux, Mercy Etoile, France) and Tempo LAB tests (automated test for the enumeration of LAB microorganisms; bioMérieux, Mercy Etoile, France).
We used the McNemar test for related samples enumeration data and Chi-square test or the Fisher exact test for independent samples enumeration data and the Student t test for independent sample measurement data (normal continuous variables) and Wicoxon Singed-Rank test for related samples measurement data.
TVC, MPN and different biochemical test were done for enumeration and identification.
