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Xiaolin Cui and Penglin Ma: Designing and performing experiments to test downstream hypotheses.
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All eight LSVDs and for comprison purposes along with two standard and high performing vaneless diffusers and one conventional vaned diffuser were tested downstream of the same impeller.
The company said it planned to have results from tests downstream at Fort Chipewyan by the end of April.
Kritzer said the state tested downstream because that's where the effects of the spill are felt.
To reduce the number of differential expression tests downstream, thereby increasing overall power, 50% of the lowest normalized Log2 probe-set intensities were removed according to recommendations by Hackstadt and Hess (2009) [49].
Osmotin by itself affected some but not all of the tested downstream apoptotic markers.
Based on our observations, PSP94 appears to function as an upstream mediator of prostasin and both proteins share all tested downstream targets.
In order to further validate the genetic interaction between VAP and TOR we tested downstream components (Fig. 5), namely S6K, Autophagy 1(and1) and Thor (4EBP1) of the TOR signaling cassette.
Here, we tested downstream signalling through p-Akt/Akt but reached no clear conclusion; thus, further studies will be needed to determine the specific route of action for these miRNAs as well as to determine their role in the other pathways containing their targets, several of which are known or suspected to influence glucose metabolism.
The more recent studies have used specific deletion strains to test for downstream components of known signaling pathways thus also identifying a relatively small number of developmentally regulated genes [8], [9].
To test the downstream biological effect of miRNAs on KLK10, we measured ovarian cancer cell proliferation.
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