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A notable application of such network simulation approaches is to test disconnection hypotheses by simulating lesions in large-scale network models and observing alterations of brain activity as a result of these lesions.
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The purpose of this study was to test for disconnection among prefrontal and parietal brain regions engaged for successful working memory performance in patients diagnosed with schizophrenia.
For these reasons, additional studies on both histone marks and DNA methylation need to be performed for this gene on the same plant material, to test for a disconnection between DNA methylation and histone marks.
This result is all the more useful because an apnea test performed without disconnection in the CPAP mode is not possible with all ventilators, especially those that do not allow inhibition of the apnea ventilation security mode in case of prolonged apnea.
The weaning was carried out by nursing staff in accordance with current recommendations [ 1], applying 1- to 2-hour-long disconnection tests with O2 administration via a T-piece on a daily basis.
Moreover, in potential lung donors, a global protective ventilator strategy that includes small tidal volumes, high PEEP, apnea tests performed without disconnection from the ventilator, and closed circuit for airway suction was recently shown to significantly increase the number of eligible and harvested lungs, although the precise role of each item has not been determined [ 9].
Introduction Primary outcome was to evaluate the efficacy of apnea test provided by ventilator disconnection protocol and O2 administration for the clinical confirmation of brain death in children.
Dr Lacroix theorizes that a RM is not useful if the apnea test is performed without disconnection in the CPAP mode.
Conclusion Apnea test performed with a ventilator disconnection protocol is efficient for brain death diagnosis in children whatever age group without serious complication.
Multiple comparisons with the sham-lesioned group (Dunnett's test) showed that only the disconnection + callosotomy group differed significantly from the sham-lesioned group.
One pertinent issue concerns the impact of fornix lesions on spatial biconditional problems, as such tasks are often highly sensitive to both anterior thalamic and hippocampal damage (e.g., [13,23,66]), including when tested in a crossed-lesion disconnection study [32], yet appear to be spared after fornix lesions [24,41,60,62].
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