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In addition, the study did not have statistically power to define a skin test cut off for incipient disease.
The best-performing training classifier included 138 genes (F test cut off, p<4×10−7) and demonstrated an accuracy of 85%.
Samples were screened for Toxoplasma gondii at Hereford PHL using the Eiken latex agglutination test (cut off titre 1/32).
Normalcy of distribution of continuous variables was assessed using the Kolmogorov-Smirnov test (cut off at p = 0.01).
This secondary analysis allowed assessment of heterogeneity between trials, defined with the χ test (cut off <10% for significance) and the I statistic (threshold of >50%).
Discrimination is assessed by measuring the area under the curve (AUC) of the plot of sensitivity vs 1 – specificity for all test cut off points.
Similar(53)
ANOVA failed in evidencing sex or M duration relationship, whereas a modest significativity (p>0.02) was related to high scores in Wang and Zung tests (cut off = 40).
31 The trial outcome was not modified when less (that is, seroconversion based on a 1 titre difference) or more (that is, higher direct agglutination test cut offs) specific criteria were used (see appendix on bmj.com).
Canine sera were assayed for T. gondii IgG antibodies by using the modified agglutination test (MAT, cut off 1 25).
We sought to determine the seroprevalence of T. gondii infection in 339 water buffaloes in Veracruz State, Mexico using the modified agglutination test (MAT, cut off 1 25).
Receiver operating Characteristics (ROC) used to establish cut off titre, was determined by plotting specificity (x-axis) versus sensitivity (y-axis) at all tested cut off titres.
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