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Among those samples, 36 patients and 7 normal samples were used as a test cohort for the evaluation of miRNA profiling.
Of those samples, 36 patients and 7 normal samples were used as a test cohort for the evaluation of miRNA profiling; 63 pediatric patients and 5 normal donors were used as a validation cohort to confirm the miRNA differential expression.
In the test cohort, for example, in 913 (ADC: 404; SQCC: 386; others: 123) cases both cores could be evaluated while in 152 (ADC: 78; SQCC: 51; others: 23) cases (14.3%) only one core was available for Ki-67 evaluation.
To validate the predictive potential of the model the determined high risk cut-off level of CRS (CRS > 6.82) was used to classify a test cohort for prognostic risk stratification.
Regarding the study design, 20 patients with CD and 19 with RA were included in the first test cohort for microarray experimentsampling at baseline and week 2. For the validation cohort, samples from 20patients with CDand 15with RAat baseline were included in the RT-quantitative PCR experiments.
(18) During April 2008 to January 2009, 38 cases were used as a test cohort for evaluation of miR-210 expression as a prognostic marker, including 34 cases with B cell precursor ALL (BCP-ALL) and 4 cases with T cell ALL (T-ALL).
Similar(54)
The endocrine-untreated arm in the Stockholm randomised trial was used as a testing cohort for BCI.
A first training cohort produces clustering and MDS coordinates results, and thereby the MDS coordinates are directly applied to the testing cohort for clustering as the prediction phase.
The model is then applied to the testing cohort for clustering as the prediction phase in Additional file 1: Figure S6(c).
In a way, this study provides the necessary testing cohort for these studies, even though under considerably tightened conditions with probable differences in surgery, in the pre-analytic steps, the immunostaining protocols, and the analytical attitude of the observers in the interpretation of immunostainings.
The table presents counts of events by type from the larger set of 75,000 patients used for sub-setting smaller testing cohorts for RetroGuide scenarios.
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