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Continuous variables were compared using the Mann–Whitney test or the Kruskal Wallis test, as appropriate.

Continuous data were compared using the Mann–Whitney U test or Friedman's test, as appropriate.

Categorical variables were compared using Pearson's Chi-squared test or Fisher's exact test, as appropriate.

Linear correlations were tested using the Pearson or the Spearman test, as appropriate.

Categorical variables were compared using the Chi-square test or Fischer's exact test, as appropriate.

Linear correlations were tested by using the Pearson or the Spearman test, as appropriate.

Comparisons were performed using Student's t test or Mann–Whitney's U test, as appropriate.

Categorical variables were compared by Chi-square or Fisher's exact test, as appropriate.

Continuous data were compared using Student's t test or the Mann–Whitney test, as appropriate.

Data were tested for normality using the Kolmogorov-Smirnov test or Shapiro-Wilk test, as appropriate.

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Data were analyzed using analysis of t-test, as appropriate.

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