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Agent-based methodologies (ABM) has caused a revolution in the area of computer modelling and simulation as we can develop models to analyse, test, predict and replicate the behaviour of complex systems.
Now before you start thinking about certain other health-related companies that wanted to skip a few steps between research and public product (cough cough Theranos), Mosa says that what MagniWare wanted to do was not come up with new, untested tech and deploy it to the public, but rather to unlock the inherent value in existing, academically tested and replicated research.
The prognostic hypothesis was tested and replicated on transcriptome data from five further publicly available data sets, confirming the association between high HJURP mRNA and prognosis.
We imputed genotypes for 4208 BCC patients and 109 408 controls using Illumina SNP chip typing data, carried out association tests and replicated the findings in independent population samples.
After imputation, the two datasets have 1,941 common SNPs in the MHC, of which 22 were successfully tested and replicated based on the statistical testing stratifying on the detailed DRB1 and DQB1 genotypes.
CIs for the indices were derived using a non-parametric bootstrap method with n=10 000 observations drawn at random from each of the itemised data sets of antibiotic prescriptions and individual susceptibility tests and replicated m=1000 times.
MANOVA analyses used PV data from each test and each replicate as dependent variables and the groups as independent variables, resulting in the model (PVs ~ groups).
In both tests, evolution regime (i.e. the isofemale line(s) on which parasites had evolved) was nested within the type of test, and the replicate within each evolution regime.
NOEC values as toxicity measures derived by hypothesis testing depend strongly on the statistical design of a study (e.g., the number of selected test concentrations and replicates), but they do not relate to an identical fixed-effect level across studies with identical designs [19].
OECD guidelines Statistical analysis and treatment of data; number of test chambers and replicates; number of embryos per replicate; if ANOVA has been used, the size of the effect which can be detected (e.g., the least significant difference).
Recently, the MicroArray Quality Control (MAQC) consortium addressed the reliability of data obtained using microarrays, by directly comparing performance across multiple platforms, test sites and replicates [ 19].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com