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In contrast, the best gain observed for the the NTP trend test was 0.048 0.5022 for the the NTP trend test vs. 0.454 for the proposed test), a modest relative gain of < 10%.
Sample-size estimates were based on a one-tailed significance test, a modest effect size (.12),.80 power, an alpha of.05, 10 independent variables in a regression equation and an estimated squared multiple correlation of.55.
In contrast, the best gain observed for the NTP trend test was 0.038 0.3311 for the NTP trend test vs. 0.293 for the proposed test), a modest relative gain of < 12%.
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Re-testing the animals 24 hr later (LTM test) revealed a modest but statistically significant retention of conditioning in ChR2-expressing animals, compared to controls as indicated by both the preference score and the difference score.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com