In addition to the timing of replication, specificities in the tertiary structure of telomeres likely contribute to the concentration of replication stress at telomeres in response to aneuploidy induction.
The function of the receptor is determined by its tertiary structure and surface features that confer specificity for ligands.
We aimed to evaluate ANCA phenotypes, kidney and patient outcome in a cohort of Central-East European patients with severe crescentic glomerulonephritis admitted in a tertiary Nephrology center in relation with ANCA specificity and histopathological classification.
This might be attributed to secondary or tertiary structure restrictions (e.g., steric hindrance), sequence specificity of insertion, or an inability to detect introns at these locations in the environment.
Aptamers are single-stranded nucleic acids that fold into defined tertiary structures to bind target molecules with high specificities and affinities.
We compared CDAD rates determined by ICD-9 codes to rates determined by C. difficile toxin assays at a tertiary-care hospital to determine the sensitivity and specificity of ICD-9 code based CDAD surveillance.
Based on the special tertiary structures, aptamers have robust binding affinity and high specificity with targets, including small organic molecules, proteins, and even cells [18 20].
Microsatellite markers have been used extensively in the primary and secondary gene pools, however, they have low transferability to tertiary gene pool species, and the lack of locus specificity hampers their application [ 26].
Unlike free RGD peptides, the disintegrin specificity and affinity is enhanced by the tertiary structure of the disulfide framework and the amino acid chain at the carboxy terminus of the disintegrin.
AT Aminotransferase HIV Human immunodeficiency Virus MeSH Medical Subject Heading NA Not available NASH Non-alcoholic steatohepatitis NS Not stated REM Random effects model SGOT Serum glutamic-oxalacetic transaminase SD Standard deviation Sn Sensitivity Sp Specificity SROC Summary Receiver Operating Characteristic TRC Tertiary referral center ULN Upper limit of normal None declared.
