Sentence examples for tertiary grades from inspiring English sources

The handling of tertiary grades is of practical importance only with respect to grade 7 cancers.

This systematic review has established the association of a tertiary grade with poorer outcome than that associated with no tertiary grade.

Several studies have investigated the clinical significance of a tertiary grade in radical prostatectomy samples.

Three studies correlated the presence of a tertiary grade with pathological stage, and six with prostate-specific antigen recurrence or clinical progression.

However, modification of the Gleason score to include a tertiary grade in Gleason 4+3 tumours might overestimate the risk of seminal-vesicle or lymph-node invasion.

A tertiary grade should, therefore, be included in the pathological reporting of prostate cancer and be considered in the interpretation and design of clinical trials.

In five studies the presence of a tertiary grade increased the risk of prostate-specific antigen recurrence after radical prostatectomy by a factor of 2·5.

In the small number of studies available, the frequency of a tertiary grade was consistently higher in samples characterised with pathological variables of poor outcome, such as extra-prostatic extension and positive surgical margins, but not lymph-node metastases.

Therefore, more evidence is needed to warrant the adaptation of the Gleason system to account for the presence of a tertiary grade, especially when scoring prostatic biopsies and applying predictive algorithms.

Prior studies assessing the correlation of Gleason score (GS) at needle biopsy and corresponding radical prostatectomy (RP) predated the use of the modified Gleason scoring system and did not factor in tertiary grade patterns.

The mean score of each domain of tertiary grade A hospitals was higher than that of tertiary grade B separately, and statistical difference was confirmed among most domains.