Sentence examples for tertiary changes from inspiring English sources

The spatial and temporal patterns of gene expression will allow us to discern some direct transcriptional responses to DLK1 and RTL1 from secondary and tertiary changes in expression due to the muscle hypertrophy.

In HbI, the structural change, although relatively localized, affects the chemical environment of the entire dimeric interface because ligand binding is coupled with a change in quaternary structure (3.3° subunit rotation) in addition to striking tertiary changes at the core of the interface.

Ligand binding in HbI is associated with localized structural transitions characterized by only a slight change in quaternary structure (3.3° subunit rotation) but with striking tertiary changes at the dimeric interface, including the movement of Phe 97 from the heme pocket into the interface.

Some concerns, however, have arisen about the validity of using the Val E11 signal as an indicator of PO2, since its intensity depends on tertiary structural changes, in contrast to the quaternary structure changes associated with relaxed (R) and tense (T) transition during O2 binding.

Salt-soluble meat proteins (SSMP) were then extracted from meat for estimating the tertiary conformational changes (hydrophobic and sulfhydryl groups).

Possible denaturation or tertiary structural changes of the protein human serum albumin (HSA) upon adsorption of uremic toxin is investigated using small-angle neutron scattering (SANS).

The ability of these excipients to prevent conformational alterations in high concentration mAb solutions (100 mg/mL) was determined by monitoring tertiary structure changes using an intrinsic fluorescence method.

The enzyme does not lose its phosphate-binding ability after substantial tertiary structure changes, suggesting that the substrate-binding region is more resistant to chemical denaturant than the other structural domains.

Circular dichroism experiments show that upon binding to PPIs, the PPI-sensitive N-terminal half of gelsolin undergoes significant secondary and tertiary structural changes that do not occur in the structurally homologous but PPI-insensitive C-terminal half.

O2 rebinding to the α and β subunits within the oxygenated R-state hemoglobin in both solutions and wet sol gels is revealed to be modulated by tertiary structural changes in two quite different ways.

When urea is increased up to 4 mol/L, pCRP undergoes tertiary structural changes that are consistent with formation of a molten globular structure; secondary structures remain unchanged indicating hydrogen binding forces contributing to helical and beta sheet structures that remain intact.