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In functional terms, we demonstrated that Nck is essential for the transport of FasL-carrying (secretory) vesicles to the cytotoxic immunological synapse [ 44].
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Although in order to help the reader to better digest the details of the introduced analysis methodology we focus on nonlinear systems without distributed delay terms, we demonstrate how the developed approach can be extended to the case of systems with distributed delay terms as well.
In our previous work, in uneventful term pregnancies, we demonstrated a higher autophagy expression in placentas obtained from cesarean section than from vaginal delivery [ 2].
In broader terms, we have demonstrated that there are statistically significant differences in local performance and global tolerance between cycles with a Class IV variant vs. a Class III/II/I variant.
In our previous study of AOM-induced intestinal tumorigenesis using a short-term ACF protocol, we demonstrated that AOM administration was associated with a dramatic increase in serum tumour necrosis factor α level 6 weeks post-AOM injection and that genetic deletion of the IL-4Rα chain was associated with raised serum IL-4 levels (16).
On the other hand, despite literature reports that institutional care has a pivotal role in long-term care expenditures, we demonstrated that institutional care interacting with higher care needs level is a relevant factor in explaining the highest LTC expenditures in our model.
Using FLAIR imaging in the preterm infants at term, here we demonstrate that abnormal low-intensity signal in the white matter predicts the neuro-developmental outcome at 6 years.
In terms of tau protein, we demonstrated that both inhalational and intravenous anesthetics produce tau hyperphosphorylation through a mechanism involving the inhibition of protein phosphatase 2A (PP2activityity by anesthesia-induced hypothermia [15].
In terms of subcellular distribution, we demonstrated that Kv4.2 is restricted to somato-dendritic domains of ITC neurons.
Using a short-term chemotherapy enrichment model, we demonstrated a critical role for nuclear bFGF in TN breast cancer chemotherapy resistance.
In our long-term NFPA proteomics program, we demonstrated DEP profile between NFPAs and controls [ 15, 35], including 50 DEPs (21 up-regulated and 29 down-regulated) contained in 72 2D gel-spots.
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