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The biological activity of obtained compounds was assessed in terms of potency (EC50) and efficacy (Emax) for arrestin recruitment.
The amino-benzosuberone derivative 4 is the most promising compound in terms of potency, stability and selectivity.
Researchers have suspected for years that NIDA's marijuana has little in common with what's available from private growers in terms of potency and chemical variety.
Several lead compounds, in terms of potency (submicromolar to low micromolar range), MAO-B selective recognition, and brain permeability, were identified.
The above mentioned compounds have shown stronger antiproliferative activities in terms of potency and efficacy upon comparing their results with Sorafenib as a reference compound.
In parallel, there is an urgent need to develop new analytical methodologies for the hit selection (highthroughput screening) and ligand binding characterization in terms of potency, affinity and mechanism of action.
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Recent military failures require us to look again at how to use the military, not to view it in terms of the potency of its hardware, whether it be drones, attack helicopters or stealth fighters.
In terms of psychoactive potency, Stamets considers the species "relatively weak".
According to mycologist Michael Beug, dried fruit bodies can contain up to 1% psilocybin and psilocin; in terms of psychoactive potency, Stamets considers the mushroom "moderately to highly active".
However, the two proteins are clearly not identical in terms of biological potency.
Taken together, this proves that statins, although classified to the same therapeutic group, differ strikingly in terms of their potency of action on the cell metabolism.
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