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There was no difference between the EcN and placebo treatments in terms of AEs, body weight, stool examinations and the assessment of tolerance.
A better safety profile in terms of AEs leading to drug withdrawal was reported in children receiving CBZ (4 %) as compared with PB (6/10 patients enrolled) and PHT (9 %) [ 4].
Despite the increasing use of SCs and hospitals' efforts to implement them, 7, 8 very few studies to date have analysed their effectiveness in terms of AEs and mortality reductions in patients undergoing surgery.
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Indeed, during the main and the recovery phase of St . Patricks Day storm several intense geomagnetic substorms occurred at high latitudes, as monitored in terms of AE and Sym-H indices (see Fig. 4).
Moreover, the similarity in the profile between the cumulative AE counts vs. strain data and the predicted crack density vs. strain by the micro mechanical model suggested for interlaminar cracking, indicates the importance of AE in monitoring the damage evolution in composites in terms of AE counts.
Chi-square tests suggested that no differences existed in terms of AE (P=0.55) occurrence between the two center types.
In terms of AE intensity, more than 88% of participants declared, when given multiple choices, that AE at moderate intensity should be the minimum target to reach optimal health benefits when exercising, both at baseline and post-intervention.
The combination paracetamol 1,000 mg and caffeine 130 mg has been proved to be superior both to placebo and paracetamol 1,000 mg in the treatment of TTH [10], at no significant cost in term of AEs, thanks to the synergistic effect of caffeine.
AE signals were then analyzed in terms of the AE amplitude, the AE count, the slope of cumulative AE count and the peak frequency.
AE signals were then analyzed in terms of the AE amplitude, the normalized cumulative AE energy, ratio of rise time to amplitude (RA) and the peak frequency.
In terms of cardiac AEs, four patients had grade 2 QTc prolongation documented in study, three in patients receiving a dose level of 60 mg or higher.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com