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We then added terms individually back into the model to see if any of the individual terms confounded the relationship between the independent variables and anemia.
Hence, GOstat identifies in total 124 unique GO_biological_process terms (confounded levels) that are overrepresented in the glu1-2 transcriprofile profile changes (Additional file 2).
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Paul Nicholls, the champion jumps trainer, was with them and all three appeared on excellent terms, confounding recent reports that their relationships had been damaged by the tensions that flowed from the disciplinary process Findlay was put through by the British Horseracing Authority.
The mystery also works on its own whimsical terms, confounding us with images of blue chalk circles drawn around innocuous objects — until a corpse turns up in one of them and forces Adamsberg to put some gumption into his vague inquiries.
Such redundant terms confound the interpretation.
In outcomes research terms, confounding bias is present when the effect of the practice variations on the outcomes of interest is distorted because of the effects of extraneous variables (variables that are causally associated with the practice variations and the outcomes of interest) [ 29].
It should be noted that in all analyses, the population term confounds any effects of year and beetle species, as well as plant population and geographical site.
In the epidemiology literature, this is termed "confounding".
In our view, the potential for allocation bias (otherwise termed confounding by indication) here is very high, i.e. that those generally less healthy patients were more likely to have been prescribed this simple-to-use once daily insulin glargine regimen than other insulins that require more frequent injections or have a greater risk of nocturnal hypoglycaemia.
Summarizing these limitations, we acknowledge that neither this study nor any individual study using observational data may adequately address the problems of endogeneity (in econometric terms) or confounding (in epidemiological terms) or establish causality.
In this particular model, the fixed breed effect term is confounded by tissue and time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com