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Based on GO terms assignment to clusters, a total of 4,678 (65%) clusters were assigned at least one GO term, among which 11% were assigned at least one GO term in biological processes, 48% in molecular function and 6% in cellular component category (Additional file 10: Figure S1).
The number of transcripts with GO terms assignment was between 54.8 60.8% (Table 4).
The customized cutoff values take effect to all kinds of sequence-similarity based analysis in TrED, such as GO terms assignment and metabolic pathway reconstruction.
Then, we describe the two competing approaches for performing the automatic GO terms assignment task: the thesaurus-based classifier (EAGL) and the machine learning classifier (GOCat).
Our study showed that machine learning approaches are now nearly able to reproduce the quality of GO terms assignment as performed by trained human curators.
Their performances were evaluated on their ability to reproduce curators' GO terms assignment, i.e. their ability to propose for a given abstract the GO terms (2.8 on average) used for curation in GOA.
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One supplementary concern about the ML classifier was: are all GO terms assignments accumulated during the past useful to profile a just published abstract?
On a short-term assignment in Afghanistan, I saw N.G.O.
Perhaps this spring, in his short-term assignment, Robinson will fashion something memorable for the long term.
A long-term assignment must be found, lest it be consigned to a Salt Lake trash heap.
Private-duty nurses are temp workers, always hoping for a long-term assignment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com