Genes containing insertions were analyzed using DAVID (Dennis et al. 2003) to find enriched annotations, particularly biological process gene ontology terms and tissue expression annotations.
The combination of the ciliary GO term and tissue expression enrichment, and the predictive capability for known ciliary and PCD-causing genes suggests that the FIGs also contain novel motile cilia genes.
The functions of the variant hosting genes are illustrated via hyperlinks to the KEGG pathways and Gene Ontology terms, and the tissue expression specificity graph.
ADSCs exert their effects at various levels, overall positively influencing the degeneration process and finally exhibiting long-term engraftment and tissue recovery.
Chronic hyperglycemia can lead to long-term complications and tissue damages such as retinopathy, nephropathy and/or neuropathy, often associated with serious diseases, which are devastating to the individual and very expensive to the health care services [ 3].
To better understand the complex interaction of the multiple variables in bladder carcinogenesis, a stochastic computer model has been formulated based on long-term carcinogenicity and tissue kinetic studies in vivo.
Using David Bioinformatics, we found a cluster of genes enriched among KEGG pathways, Gene Ontology terms, and the Uniprot tissues related to immunity and autoimmunity (Supplementary Information).
To capture common pathways, we analyzed overlapping GO terms across tissues and species and conducted hypergeometric testing to assess the significance of overlapping pathways.
Conclusion: An endogenous nitric oxide system is present in the uterine cervix at term, and this tissue is responsive to nitric oxide, which causes relaxation of the cervical muscle.
In addition, 16 tissues subjected to various treatments [ 33] were sampled indicating that it is a broad sampling of the transcriptome in terms of tissues and developmental stages sampled.
