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In these charts, each life is represented by a line whose terminus shows the age of the victim when she was killed.
The exposed bedrock downslope of the glacier's terminus shows the effects of glacial plucking.
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The purified TEVp mutants fused with double hexahistidine-tag at N and C terminus showed highest yield, solubility and cleavage efficiency.
In contrast, a domain of similar size at the COOH terminus showed only 57% conservation of primary structure between the two proteins.
A previous study [2] using chicken anti-BORIS antibody and a 5' end-labeled BORIS probe, both specific for the N258 terminus, showed that expression of the BORIS B0 isoform was restricted primarily to spermatocytes.
Experimental localization of nuPsb28 fused with yellow fluorescent protein (EYFP) at its C terminus showed that the protein is located inside the diatom complex plastid, in agreement with the in silico predictions (Figure 4).
Surprisingly, loss of the GR NH2 terminus showed transactivational enhancement by MNAR overexpression.
On average, 67% of the events were associated with more than one functional event, and alternative N- terminus showed the largest overlap with other functional predictions.
E2F1 has typical domains for its transcription factor activity including, DNA-binding domain (DBD) next to the N terminus, and transactivation domain (TAD) located in the C terminus (shown in Figure 1).
An attempt of such prediction would require also incorporation of the amino terminal domain of the receptor (absent in this model and in many crystallographic structures of GPCRs; CCK-2R N-terminus shows no significant homology to any protein found in the PDB database [39]).
Interestingly, the N-terminal portion of nucleolin can bind to DNA and histone H1 [59] and the C-terminus shows a helicase activity [60].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com