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The Straight Cut design features a circular distal terminus designed especially for type B dissections, whereas the Free Wire design allows a safe and secure anchoring mechanism while ensuring blood flow into the existing branch vessels.
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Here we report that A3G with a double W94A/W127A substitution in its N-terminus, designed to abolish RNA binding and protein oligomerization, alters the DNA deamination specificity of the enzyme from 5′CC to 5′TC on proviral DNA.
An internally quenched decameric peptide substrate containing a phospho-tyrosine residue, labeled with PtCP-maleimide and dabcyl-NHS at its termini was designed.
Novel amphiphilic poly 2-oxazoline)s bearing l-poly 2-oxazolineties at the alkyl side-chain termini were designed and synthesized bearingttom-up protocol.
In this study, three alamethicin analogs possessing a charged residue (His, Lys, or Glu) on their N-termini were designed with the expectation of stabilizing the transmembrane structure.
In an effort to improve biphalin's potency and efficacy at the µ- MOR) and δ-opioid receptors (DOR), a series of cyclic biphalin analogues 1–5 with a cystamine or piperazine linker at the C-terminus were designed and synthesized by solution phase synthesis using Boc-chemistry.
C-probes with allele-specific termini were designed as described earlier [ 1].
In the present work, two series of B1 analogs with different substituents on the N-terminus region were designed and synthesized.
Naphthalene diimide having two dicobalt hexacarbonyl complexes at its substituent termini 1 was designed and synthesized as an infrared probe for double stranded DNA.
In effect, the dnMSTAT construct is a protease-resistant inhibitory propeptide lacking the biologically active C-terminus that is designed to inhibit endogenous myostatin.
The N-termini for all designed peptides were acetylated using 20% acetic anhydride in DMF.
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