Further support for this double-hairpin (or paperclip) model was provided by FRET measurements in which donor and acceptor fluorophores in the repeats and in the termini came into close proximity.
Whereas the tail structure of XRCC4 comprises an elongated coiled-coil, the equivalent extended helix α4 of XLF is followed by further helices, α5 and α6; these fold back around the coiled-coil formed by α4 so that the C-termini come close to the α1 helices of the head domains.
And when the tunnel's terminus actually comes into view, he added, "it's likely we'll get a muted recovery, rather than leaping back".
If life can only have one destination, then, Burkeman argues, we should enjoy the journey as much as we can and deal with the terminus when it comes.
Burkeman's conclusions are best expressed in a quote he uses from the Chinese philosopher Lao Tzu, who once wrote: "A good traveller has no fixed plans and is not intent upon arriving". If life can only have one destination, then, Burkeman argues, we should enjoy the journey as much as we can and deal with the terminus when it comes.
Following a turn to the north, the route comes to its terminus at an intersection with DE 26 to the west of Millville.
After crossing the rail lines, SR-202 intersects with I-80 near the Great Salt Lake State Park and comes to a terminus at the I-80 frontage road, which provides access to the Great Salt Lake State Park and to the Saltair resort.
When Kingsand becomes County Route 644 at the intersection with Cathedral Avenue, Route 7 turns north from Kingsland onto Cathedral Avenue and comes to its terminus at Orange St in Nutley.
The route meets a westbound exit and entrance for the Lincoln Tunnel Park & Ride and comes to its terminus at a traffic light with U.S. Route 1/9 south, with no direct access from Route 3 east to U.S. Route 1/9 north.
This is where NY 45 comes to its northern terminus at US 202.
